Lieve and Agate – hi, thanks for all the useful info on Letrozole. May I ask if either of you know whether this may also help those of us with PID? (I’m never sure whether endometriosis and PID are the same thing, or whether one is a subset of the other, or whether they’re different altogether …. After my lap, my doc said I had PID but not endo, though I’ve read that some doctors don’t distinguish between them?)
Hi sofagirl, it is not really that Letrozole helps
against a disease, it is mainly used in cases where women have repeated RIF (Recurring Implantation Failure) and RPL (Recurring Pregnancy Loss). It is thought that
most of those women have endometriosis probably, even if it hasn't always been (correctly) diagnosed and even if some women don't even have symptoms or only have it mildly. I see you have already done a laproscopy and it may well be you had PID because of f.ex. Hidden C. There are various reasons for getting PID, endometriosis and/or endo related infections is one. Are you sure it is 100% ruled out you have endo at all? Even mild endo?
I have severe endo myself and I have also had PID (Pelvic Inflammation Disease), where an endo cyst got infected inside my ovary. I nearly died because of this in 2010, as I was incredibly sick and no AB would help (long story). I dont have Hidden C.
Lieve – did you decide to do the etegrity test in the end? (Or are you just assuming that your beta3 levels are low because of the endo?)
What Letrozole does for women with RIF or RPL is to correct the
lack of a glue-like protein - the beta3 integrin - that women need for embryo implantation to be successful. The only way to find out whether you lack this specific protein, is to do the Etegrity test. But you can also argue that if you have RIF or RPL and also endometriosis, you are probably going to test negative for the presence of the protein in question. As I have endo + RIF, it is very likely I lack this protein. So I have convinced Penny to include Letrozole in my protocol. If your profile is more complex, it might be a good idea for you to do the Etegrity test, especially if you still
could have endo. The Etegrity test is so you will have documented you lack the beta3 integrin.
This link might be helpful:
http://ghsfertdoc.wordpress.com/2010/03/10/implantation-failure/If you search for other topics, you will find more on the effect of Letrozole for RIF etc. too.
Quick question to any of you who have seen Trevor Wing – I have an appointment with him later this week, and I can’t decide whether or not to keep it. I’d be really interested to hear of anyone’s experiences of a consult with him. Is it just the mushrooms etc. he would advise on, or is it broader in scope than that? Before Christmas Penny seemed to be recommending him to me very enthusiastically, but a couple of weeks ago when I asked her again, she suggested going straight to her man in Malaysia. Can’t decide if a consult with TW will be a waste of money, and like most of you, I’m sure, we don’t have the spare cash available to spend it on a whim!
I went to TW and I thought he was such a nice & knowledgeable man. He has helped many women. My case is so incredibly complicated, that he never suggested any treatment for me. It ended with that he now suggests a mushroom treatment that he admits he actually has not much experience with yet in his practice and that may or may not work. So I am not sure tbh.... But if your profile is not too complicated and you know what your issues are, he is more likely to help you - in my opinion.
I dont know what Penny is telling you to get from John in Malaysia? Is it Cordyceps? As there are other mushrooms/herbs out there for different fertility related issues, like Coriolus and Reishi or even others that are not as famous as Cordyceps etc. If it is not too difficult to get to Richmond and you would like a more specified opinion on herbal/mushroom treatments (or conventional western med), I actually think TW is a really good person to go to. Sorry if this is confusing you even more!!
Good luck xx
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