* Author Topic: Immune issues - start here guide to this section!  (Read 141761 times)

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Offline Bexter

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Re: Immune issues - start here guide to this section!
« Reply #90 on: 5/08/13, 18:27 »
Agate

You were right - Penny has increased dose to 2  x 40 - thank you so much!
Bex x

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    Offline poppyseed1

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    Immune issues - start here guide to this section!
    « Reply #91 on: 22/01/14, 20:25 »
    Hello!
    So I'm looking for some advice.

    I've had 3 misscarages in 12 months
    "Baby" not progressing from 6 weeks is the issue for me.

    Any tips or advice as to what might be going on

    With huge thanks xx 


    Offline Fishes

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    Immune issues - start here guide to this section!
    « Reply #92 on: 23/01/14, 04:00 »
    Sorry to here that poppyseed you have been through so much.
    I dont really have any answers, do your clinic think its immune related or an embroy genetic issue?

    X

    Offline agate

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    Immune issues - start here guide to this section!
    « Reply #93 on: 23/01/14, 07:38 »
    hi poppyseed:  i'm sorry for your miscarriages.  you might want to look at the miscarriage section of faq.

    early miscarriages can be difficult to tackle because its hard to know the reason, but common reasons are:
    - hormonal e.g. low progesterone
    - infection e.g. chlamydia, mycoplasma causing hostile uterus and/or poor sperm quality
    - genetic e.g. a permanent problem with your or your partner's karyotype, or a variable problem with the egg or sperm quality
    -anatomical e.g. a septum or fibroid in the uterus
    -bloodflow e.g. due to scar tissue in the uterus, or a thrombophilia
    - immune e.g. raised NK cells or inflammatory cytokines causing problems with egg quality or hostile uterus

    basically, the approach most good doctors will use is to prioritise those according to your history and investigate them to see if they can cross any off... then try to treat you according to what they find.

    Offline Fishes

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    Immune issues - start here guide to this section!
    « Reply #94 on: 23/01/14, 08:54 »
    Hi Agate,

    Could I please pick your brain?

    I read somewhere that chocolate was a no no with immune issues and have not had any for months!!!!
    I have raised helper cell ratio and slightly raised killer cells, should I say away from
     Chocolate, or have I made that up?

    Hope your well


    Offline agate

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    Immune issues - start here guide to this section!
    « Reply #95 on: 23/01/14, 12:17 »
    I THINK chocolate is a mixed bag because you are talking about a product made of
    sugar (mainly glucose, some lactose if its milk)
    fats (mainly saturates)
    milk proteins (if its milk)
    cocoa solids

    the sugars and saturated fats probably aren't helpful to anyone.
    the cocoa solids will contain very variable mixes of flavinoids depending what brand you buy (the cheaper brands tend to have very little cocoa in anyway, and the 'premium milk' brands will tend to have the cocoa doctored to remove the bittterest flavinoids, but anyway....

    studies showed that some of the flavinoids boosted immunity and some suppressed it, so its probably russian roulette depending which brand you happen to buy?

    Offline Cloudbaby

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    Immune issues - start here guide to this section!
    « Reply #96 on: 8/02/14, 09:52 »
    Dear Agate

    I have woken  to my sixth BFN this morning. I was hoping to talk to you about what to do next as I've had a lot of immune testing done already, but not sure what board is best to chat with you on. Please point me in the right direction.
    Thank you so much

    Offline agate

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    Offline Cloudbaby

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    Immune issues - start here guide to this section!
    « Reply #98 on: 8/02/14, 10:58 »
    Dear Agate

    I wondered if I could seek your advice, as I feel very lost.

    2009 ICSI - admitted 2wks in hospital OHSS
    BFP - 2010 First FET (have our son)
    Since then

    Four FET's same batch as BFP all BFN's
    Fresh Cycle - BFN bled early before OTD
    Two subsequent FET's both BFN

    I have had various immune tests done, including; vit D, Thrombophilia screening, anticardiolipin antibodies, lupus anticoagulant, natural killer cell, coeliac antibodies, and anti thyroid bodies. My NK cells were border line, my thyroid TSH high, but I have got this now down to 1.6. On my last cycle FET I was taking 10mg Prednisolone. The last two FET's I have had an endometrial scratch done.

    Our embryos are always very good (told top grade) and have achieved  good fertilisation rates. But still not working.

    Do I:

    1.) Continue Russian roulette with our two remaining frosties ?
    2.) Have  fresh cycle with PGS which has been suggested?
    3.) Try a local clinic which is round the corner outside London but doesn't specialise?

    I feel our chance to give our son a sibling is slipping away completely. Do you have any suggestions??

    Your trouble and time in replying would be very much appreciated.


    Offline agate

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    « Reply #99 on: 8/02/14, 13:57 »
    what was the lining like?  what prep protocol did you use in the last few times?   how old are you?  is there signficant male factor?  are the embryos blastocyst?  what luteal support did you use?  do you have pcos?   has your weight/diet changed much since when you got pg last?