* Author Topic: Cancelled due to non-response  (Read 1387 times)

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Offline Links

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Cancelled due to non-response
« on: 31/03/14, 16:51 »
Hi Ladies,
Does anyone have any advice? I have FSH of 7.8 (previously as high as 14) and AMH of 5.2 and am 38 years-old. In Jan I started my first ever round of IVF. Obviously they expected me to have a poor response so I was started on 6 vials of Menopur (plus Cetrotide later on). My response was so slow that after 11 days and when one follicle reached 17mm they cancelled (the doctor doing the scan actually asked me if I had been taking the meds!!). I have the follow-up appointment on Thursday and am wondering what to expect. I am going through NHS and have been approved for three rounds. So my question is this… since they put me on the max dose from the start are there other things they will try? Or is it possible they will decide not to offer any more IVF?
Has anyone had an experience like this?
Many thanks!

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    Offline Molly99

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    Cancelled due to non-response
    « Reply #1 on: 31/03/14, 17:12 »
    Hi Links, I don't really know about NHS treatment (we don't qualify as DH has children) but I have a very similar FSH and AMH.

    I did a lot of research about IVF with a low AMH and read a lot about mild IVF.  We went with this in the end as it is kinder to women with a low egg reserve and concentrates on quality rather than trying to force loads of numbers, which can often end up with a low response.

    Maybe have a read up about it and ask the clinic whether they think that this would be an option for you?

    I hope that you find some answers on Thursday xxx

    Offline Links

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    Cancelled due to non-response
    « Reply #2 on: 31/03/14, 17:21 »
    Thanks Molly! I'm so sorry it seems to be the end of the road for you.
    I will be sure to ask them about mild IVF - I was on a short protocol so maybe it's similar? I guess I'm worried that I will go in on Thursday and they will tell me there is no point in continuing!

    Offline Molly99

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    Cancelled due to non-response
    « Reply #3 on: 31/03/14, 17:32 »
    Oh no Links.  If they tell you that there is no point then walk straight out of there and find a better clinic.  There are always options, we've got a lowish AMH but it isn't non-existent and there's still enough there to work with.  Your FSH is good!

    I think that the NHS is a bit more traditional sometimes but I think that a short protocol is probably similar to Mild IVF, though I'm not absolutely sure.  6 vials of Menopur sounds huge compared to what I was on, I only went through 1 vial over 9 days.

    Thank you for your kind thoughts.  Wishing you loads of luck x

    Offline BettyMax

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    Cancelled due to non-response
    « Reply #4 on: 31/03/14, 20:54 »
    My second cycle was abandoned due to no response - I was on the max menopur too. After doing some research I felt that sometimes for "poor responders" blasting the ovaries with a high dose is not the best way to get a response. I got a  better response the first time (although still low) on half of menopur!

    Our next course was to look at mild IVF or egg donation. Although, as you can see from my ticker, nature has intervened! Even with an AMH that was almost undetectable there is hope.

    Offline mmummy

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    Cancelled due to non-response
    « Reply #5 on: 1/04/14, 11:07 »
    Hi Links,

    My AMH/FSH is similar to yours, and i'm 41.  I went private through ARGC, who did bloods daily to check how i was responding.  I was on clomid, cetrotide & viagra as well as high doses of merional/fostimon.  My merional/fostimon changed daily (some days only one of each, some days both).  On my highest dose day, i had 750 of merional plus 300 of fostimon.  Until then, i'd understood that the 'max' was 600 of only one of them.  This was all on short protocol (which means you start just after A/F), but it is not mild - mild is very little stimulation/drugs, but aiming for one good quality egg.

    Although at day 8 i only had one follicle that was starting to grow (and it was still only about 15mm by day 11), by EC on day 17, i collected 10 eggs.  6 fertilised and i've now got 3 onboard (2WW).   

    i think your challenge may be finding somewhere that is willing to tailor the treatment to you specifically, which I'm not sure will happen on NHS (but i note that i've never done nhs ivf so i don't actually have an informed clue!).  Best of luck.

    Offline Links

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    Cancelled due to non-response
    « Reply #6 on: 1/04/14, 17:05 »
    Thanks Betty - always encouraging to see things worked out for you  :)
    And BEST of luck for the TWW MMummy! If I get to that stage I imagine I will be a total mess of anticipation!