* Author Topic: Low AMH / High FSH Cycle Buddies - Part 6  (Read 126990 times)

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Offline queenie123

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Low AMH / High FSH Cycle Buddies - Part 6
« Reply #1780 on: 12/01/19, 20:41 »
Helen - It depends why you are taking it, 5mg is enough for an anti-inflammatory effect and it also helps a little bit to prevent premature leutinisation.   It is not enough if you have proper immune problems - have you had immune tests?
Penny puts everyone on a low dose if you are going to have a transfer, anecdotally I do think 5mg makes a slight difference for me. 

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    Offline Sunshine122

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    Low AMH / High FSH Cycle Buddies - Part 6
    « Reply #1781 on: 12/01/19, 20:45 »
    Helen, Create do 20mg prednisolone from EC until ET, then change it down to 10mg, said I could stop from BFP although I havenít and am still on 5mg.

    Offline Helenbeau

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    Low AMH / High FSH Cycle Buddies - Part 6
    « Reply #1782 on: 12/01/19, 22:47 »
    Help...any body used Bemfola before? Just gone to take my first Bemfola injection and I think they pharmacy has sold me the wrong injection pens. Itís a 450 pen and I only need 150 but the dial only goes as low as 300. I turned it to 300 and just tried to inject half...not very accurate. Not sure what else I can do? 🤷🏻‍♀️ The pen says itís to be used once so Iíll just have to clean the needle. Am I being dense? Not sure if I need to try buy some new ones now but I really donít want to. I got them from fertility 2 U so wouldnít be able to get replacements before Tuesday.

    Offline queenie123

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    « Reply #1783 on: 12/01/19, 23:09 »
    Helen,
    I have taken Bemfola before and also only used half the amount.
    I am sorry the pharmacy messed up - clearly they did.

    It is possible to use a normal needle and syringe and draw it up into the new syringe, change the needle and use it on yourself - but it is very fiddly, and you need to know the iu/ml in order to be able to convert it.   Do you have a selection of spare needles and syringes? Many pharmacists will be able to help sell you some if you explain why. 
    I can't remember exactly how I did it, but I think it involved pushing the new needle through the plastic bit at the top and drawing up the medication, just before I wanted to use it. 

    No you are not being dense - it isn't like the Gonal-F syringes which are multi-use the Bemfola ones are single use.

    Offline Helenbeau

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    « Reply #1784 on: 12/01/19, 23:53 »
    I have needles and syringes but I still have no idea of the volume I should draw up. Iíd have to empty a complete pen into a syringe and then measure volume and divide by 3. But Iím worried if I mess around with the solution it might ruin it. What a pain. Iíd Bemfola the same as gonal F?
    I thought the pharmacy had made the mistake but Pennyís prescription actually say 450iu vials x 3, so I canít really complain to the pharmacy and try get a refund. Such a pain.

    Offline queenie123

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    Low AMH / High FSH Cycle Buddies - Part 6
    « Reply #1785 on: 13/01/19, 00:14 »
    Helen - how did you get Penny to give you a script for Bemfola?  I have not managed to get her to do it, despite the fact I respond so badly to Menopur at the start of the cycle.

    Yes Bemfola and Gonal-F are virtually the same thing - different manufacturer.

    Anyway,  I think you can double check on the label on the side - but 150iu is normally 0.25mls, so 300iu is 0.5ml etc.

    I would only draw it up immediately before you need to use it so it is not in the other syringe for long, and make sure you can't re-use them first, (I am 95% sure you can't - but it's from memory).   

    If you have a choice and plenty of money then obviously it goes without saying it is better to get a new script and the correct dose pens - but if you can't get anymore it is possible, just very fiddly.

    Online Briss

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    « Reply #1786 on: 13/01/19, 09:37 »
    Just a quick update apologies for lack of personals. Looks like long protocol might actually be OK for me because after 10 days of stims with 225 pergoveris I have overall 6 follicles out of which 3 look like real contenders 20, 19, 16. There is also 13 mm one but I think it's too small. Although Munich only does one measurement so not sure how this compares to my usual scans that provide an average of 2 measurements. Still, The growth spur is quite dramatic from 10mm on day 10 to 20mm on day 14. Naturally my follicles do not grow this fast. Also they don't reach 20mm! I'm just waiting for my today bloods to be told whether we trigger today or tomorrow. I relinquished control of this cycle on purpose. It's been my experience that I draw wrong conclusion on stim cycles and make poor choices. My body behaves differently on stims so everything I know about myself from natural cycles is not always relevant.  It's not an easy decision but I feel placing my trust with Munich on this particular cycle is less risky than relying on my own judgement.  But of cause it's a risk anyway and I'm nervous. I only left myself a monitor and I know it didn't detect the surge yet. Also my sex drive kicked in yesterday so my estrogen must be high now.  Just trying to stay calm and hope things will work out. Of cause the real test of whether this protocol works for me is not just whether we are able to get the eggs out on time or the number of eggs but if any fertilise. So far the only stim cycle where I achieved fertilization was estrogen priming protocol with elonva and Menopur. Out of 20+ cycles this was the only time I had more than 1 embryo to transfer.

    Offline Babyhopeful

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    « Reply #1787 on: 13/01/19, 11:10 »
    Helenbeau- I use Bemfola and Iím pretty sure theyíre only single use pens. I know the 450 ones are pretty expensive, so if you are able to split the dose as Queenie suggests, that would be the best way forward. As for spoiling the contents of the syringe I think as long as the Bemfola is kept refrigerated until itís ready to use, it should be fine. I was on 10mg of prednisolone from EC to 9 weeks, when I began tapering off. Next time Iíll be on 20mg.

    Briss - It sounds like your cycle is going well. I never know my oestrogen numbers as my clinic just goes on follicle growth and size. 3 good sized follicles sounds amazing! I wish you lots of luck for EC later this week.

    Queenie123- Congratulations on your 3 day transfer. 3 day transfers are my favourite. I think my on my first 3 day transfer the embryo tried to implant (unfortunately the clinic gave me an incorrect dose of progesterone) and my second resulted in the recent pregnancy. In the future I wonít hesitate to have another 3 day transfer. Iíve been reading a bit about low amh women, apparently it can be difficult to get pregnant naturally as our hormones are often all over the place. Hopefully this issue should be resolved with ivf cycles where our hormones are more controlled. I think for me insufficient progesterone after ovulation is the main reason for my inability to conceive naturally. From now on Iíve decided that all my natural attempts will be using cyclogest after ovulation.

    Sunshine122- Iím so glad your scan went well, Iíve been thinking of you. 1 day is neither here nor there, so I wouldnít worry about that either. It sounds like you have some nice strong pregnancy symptoms too.

    Klik- Thank you for your kind words. This week alone my hairdresser and reflexologist have opened up about their miscarriages. My reflexologist had 3, but now has 4 healthy boys. My hairdresser went on to have a successful pregnancy after her miscarriage too. Although neither were going through IVF it gives me hope that a healthy pregnancy can be achieved for us all. I totally understand your feelings at the moment. I hope there will come a point when you can relax into the pregnancy.

    Shadywheat- It is frustrating waiting for my body to return to normal. It is getting there, but not quick enough for my liking. Iím going to check for ovulation this month  and perhaps try naturally with a bit of cyclogest. Iím glad you had a warm welcome back at your clinic. A friendly clinic makes such a difference, thatís one of the reasons we like ours. The sketchbook challenge sounds a lovely idea.

    Katkat - Iím glad you enjoyed the skiing despite some members of your family. I had never heard about the embryo fragmentation issue before. I also thought it was more to do with the egg quality. My consultant likes to keep up to date with findings and techniques, so there must be something out there to support it.

    Jeb1982 - Welcome! Iím still having stims cycles at the moment. I have had fairly good results with DHEA and increased protein when stimming. Iím planning to continue using these for my next treatment cycle.

    Afm - I plan to return to work tomorrow. Iím feeling a bit apprehensive, but I know it will be good to get back into a routine and have something else to focus on. Iíve started doing yoga again and dug out my goggles, so I can start swimming again in the next week or two. Iím also giving my diet a bit of an overhaul, in that Iím cutting back on dairy and gluten. Iíve read somewhere that this can help with DOR. I donít think itís feasible to completely cut out diary and gluten, but Iím aiming to follow this diet for at least breakfast and lunch. Itíll be interesting to see if there are any improvements to my response when stimming.

    Offline katkat2014

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    « Reply #1788 on: 13/01/19, 11:46 »
    Shady how much and dosage of progesterone will you be on? What day will you check the lining? Also just modifying to add, will you take HCG booster shots?

    Helen is it really that bad to just reuse the same needle again?I've done with with most of my clexane injections and I am still alive. Although stims may be different of course.

    Briss that's a great result, fingers crossed!

    AFM I really want a thicker lining this time! Have I covered everything: beetroot Juice, legs up the wall, castor oil packs, warm feet/socks, multivitamin with 150iu selenium, 1000 vitamin E, 1000 l-arginine, raspberry leaf tea. Anything else? I will take 2x progynoa orally per day and 2x skin sprays of lenzetto per day. Should I replace progynoa with estrofem and take the evening one vaginally?

    Offline Helenbeau

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    Low AMH / High FSH Cycle Buddies - Part 6
    « Reply #1789 on: 13/01/19, 19:27 »
    Hi Kat, wow I really think you are doing everything there for your lining. Canít really add anything except I have some viagra gel if you want some? Not sure if it makes a difference.
    I donít care about using the needle more than once, the problem is thereís no way of knowing how much Iím injecting.
    The solution Iíve found is to draw out the contents of the pen syringe into another syringe with measurents on it. So I can kinda tell what Iím injecting now and I just have to keep it in the fridge. Not ideal as I seem to lose a bit every time in the syringe but thereís no way Iím wasting what I have. Thanks Queenie for your suggestions xxx