Thanks both,
Serum doesn't do MACS - their embryologist is doing a clinical trial on sperm selection, I am not sure what she does but it involves them swimming through something (similar to PICSI). She is patenting it, and I think it is amazing. My DH had a very high DNA fragmentation, after her protocol it was down to between 0-1% - that is miraculous.
I have never had a positive outcome with MACS, and Penny feels that it can damage sperm, which given my embryo's arrest on day3 at Reprofit (which is when sperm kicks in), when we have MACS, I can't help but agree with her.
Briss - You need some drugs now (in my opinion), I did a nearly natural cycle with Serum, everything natural until day 9, then we added in a little stims and cetrotide, (started both early so Penny can control it, keep the LH low, and the stims replaces your natural one), it allows you to get optimal timing. It works really well for me, it is the combination of allowing your body to select the best follicle, not pushing your ovaries, but also controlling the ovulation and your FSH.
As we age our natural LH gets higher and less effective - the Pergovaris does help with this, I had a good(ish) cycle at reprofit which was down reg with Oestrogen and Testosterone - the T gives you more follicles and the E keeps your FSH down. Then low dose Pergovaris (<100IU) for stims. Which has a better LH for people like us. But even though I made 2 good d3 embryo's they did not develop past d3, which I feel was not the eggs, but the way they 'clean' them, or the MACS??? (Unsure, it doesn't make sense - when serum embryo's don't arrest then) - anyway, the point is I think the stim protocol was good for me, and would likely be good for you. they also add in a little bit of Letrazole for people who need it to help delay LH.
Ask me anything you want about Stem cells - I had it done at Serum, and it did make a difference but only for a few months.
P has increased the protocol and new it includes a matrix so it costs €7k. I figured out that I could have 4 cycles for that (at Serum), so for me keeping on going was the better option. She does proper stem cells though (not PRP).
Dorchester - You can downreg with Oestrogen which helps you stop having luteal phase follicles. It sounds like your ovaries need a month off - I found that Macca and Agnus Castus helped normalise my cycle length and perpare me for a natural cycle. It has sucessfully dropped my day3 FSH to 8 (from 20ish).
Briss is right, Progesterone can be used to decrease LH later in the follicular phase, but it isn't great - CRGH do this routinely.
You could also try letrazole for day 1-5 as it decreases your Estrogen it delays your LH rise.
Although Dr Gudi might be a good fit for you.
