ML, hi, and yes I take your points completely.
I agree with you that chromosomes are key for us. absolutely.
However, something I have observed and find difficult to explain away is that many many women on FF of all ages end up with eg only 2 blasts from eg large nos of fertilised eggs. (Im ignoring the poor medical management issues when eg women are allowed to develop 30 follicles, 20 are collected and only 10 fertilise.)
Now, YOUNG women with their 2 blasts often get bfps notwithstanding lowly graded embryos. (ie what the embryologist can SEE, not chromosomal analaysis) whereas OLDER women with perfect blasts - superficially - get nowhere. This all indicates to me that the younger women's eggs have significant potential and any LACK of development (the reduction from the number of fert eggs to eg 2) is down to being significantly compromised by coming out of the body. (now, logically, the only other explanation i have for the tiny number of blasts is that even younger women only produce circa 2 good eggs each cycle - it's possible but unlikely as there is no indication whatsoever in medicine that this is right.)
Some of this lack of success for older women is down to poorer receptors and interactions witin the uterus, undoubtedly and some also stems from immune issues. The rest is chrom related. Therefore it makes more sense to me to get as many back in, trying to implant (to find this elusive good egg) than to risk any further stress on the fert eggs. After all, no clinic tries to say the fert eggs do BETTER outside the body do they?
Lastly, we should be sensitive to the fact that clinics' success rates improve dramatically with blasts - but it is just stats! they should compare implantation rates day 3 as a % of eggs fertilised with implantation rates day 5/%eggs fertilised for a proper comparison.
I for one this next time will do day 3 transfer of what looks best (and out of my probable 10 fertilsied, it isn't that hard to analyse, once you take into account where they are now cellwise, gradingswise, which have been on track on along, which had vacuoles at collection etc.) Day 3 last time I had 8 grade 1, 8 cells but when you apply the other parameters, you very quickly get down to the likely best two. i would then freeze the remainder and try FEt the following months rather than pot luck of another ivf.i have very few concerns with the freezing process as my clinic (lister) is fine on this. Im also aware that the stimms rocess and conmmensurately high E2 that develops, can prevent implantation and so i would do an unmedicated trasnfer the following month and hopefully the month after.
very best of uck with your 11 ML -

for you and do let me know how you get on as I will you too with my apporach. one way or another we'll get there! xxx