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Donor screening at ManorIVF

2K views 2 replies 2 participants last post by  ManorIVF-UK coordinator 
#1 ·
Another very important issue we are always being asked about is the Donor screening.
This is very important issue as we understand egg donation recipient want to know that the donated egg they receive are from healthy fertile donor and I am sure they would like to know the donor was happy to donate her eggs and was treated as someone who gives the gift of life.
At ManorIVF We adhere to both ASRM (American Society for Reproductive Medicine) guidelines and our own institutional ethics board, thus making sure every egg donor is acting of her own free will and volition without being coerced in any way and that she is not donating for financial reasons. We will not accept a donor who had not undergone a comprehensive evaluation by a psychologist as well as all the required mental and physical tests.
we have the same level of responsibility to both our recipients and donors. Our oocyte donors receive the same individualized attention and clinical vigilance from our team.

1. Current Manor IVF Donor Criteria
 Oocyte donation may or may not be anonymous, depending on the circumstances
 Donors donating to UK based patients are consented to be identified (HFEA requirement)
 A five family limit is applied
 Psychological evaluation and counselling by a qualified mental health professional is stronglyrecommended for the oocyte donor and her partner (if applicable)
 Oocyte donors will be between the ages of 21 and 34
 Proven fertility is required.
 The donor should undergo appropriate genetic evaluation based on medical history, in accordancewith ethnic background and current guidelines. All donors will undergo cystic fibrosis and karyotype testing
2. Medical Review:
Donors will be healthy and not be carriers of hereditary diseases. A complete personal and sexual history will be obtained to exclude individuals who might be at high risk for HIV, STDs or other infections that might be transmissible via gamete donation. Donor will fill Medical and Genetic Health Questionnaires. Donors are routinely tested for: Sexually Transmitted Diseases (STDs): HIV 1 & 2 Hepatitis B surface antigen (HBsAg) Hepatitis B core antibody (anti-HBc IgM) Hepatitis C (HCV) Syphilis (VDRL) Cytomegalovirus antibody (CMV IgM, IgG) Genetic conditions: CF FRAX Karyotype Immunohematology: Blood group Rhesus factor (Rh) Thalassemia minorHaematology: Red blood cells (RBC) Haemoglobin (Hb) Haematocrit (PCV) Mean corpuscular volume (MCV) Mean corpuscular haemoglobin (MCH)
Mean corpuscular haemoglobin concentration (MCHC)
Gynaecological check-up:
Ovaries assessment and antral follicle count (trans-vaginal ultrasound)
Hormone profile:
Anti-Müllerian hormone (AMH) (ovarian reserve)
Follicle-stimulating hormone (FSH)
Estradiol (E2)
Luteinizing hormone (LH)
Following are the areas on which donors will be questioned:
 Extended family medical history (parents, siblings, grandparents, great-grandparents, uncles, auntsand first cousins)
 Own medical history (including allergies and medications)
 Alcohol consumption, use of illegal substances and smoking (donor and family members)
 Gynecological history (including previous donations and pregnancies)
 Children's health and development
 Psychological profile and practical issues linked with donation
 Education, grades, achievements, profession, special talents and interests
 Phenotype of donor, her parents and siblings (eye colour, hair colour and texture, skin colour,height, weight)
 Donor's family origins and genealogy, race, body type, religion, vocational dispositions
3. Physical examination: All donors shall undergo a detailed physical examination, pelvic exam, scan and STD screening (gonorrhea and chlamydia)(gonorrhea and chlamydia)ning (gonorrhea and chlamydia) ning (gonorrhea and chlamydia)ning (gonorrhea and chlamydia)ning (gonorrhea and chlamydia)ning (gonorrhea and chlamydia)
4. Egg collectionThe egg retrieval procedure takes place in the morning, approximately 36 hours after the ovulation injection, and lasts less than 20 minutes. It is a minimally invasive, ultrasound guided transvaginal follicular puncture to collect the eggs. The anesthesiologist puts the donor under light general anesthesia (Propofol) for the length of the procedure, so that she will not experience any pain.
5. Post Egg Collection Donor Monitoring:
Following their egg collection, donors will be monitored in a private recovery area for approximately 2 hours. Donors will need to be accompanied by an adult for the first 24 hours following the procedure. Donors will be monitored for OHSS. Donors will be stimulated using the antagonist protocol which will enable the use of GnRH agonist trigger to minimise the risk of OHSS.
Manor IVF will reimburse donors and their companions' accommodation costs for up to the first 48 hours following the procedure.
Donors shall be informed about potential side effects (bleeding and discomfort) and instructed to use pain
killers if necessary (donors will be provided with an information sheet to guide what symptoms they should look out for and instructions to call us immediately if they experience any of them). All donors will be given an emergency number and should contact the clinic immediately if they experience one or more of the following symptoms: fever, fainting, abnormal vaginal bleeding, extreme weakness and/or severe nausea or vomiting. Alternatively, donors may report ASAP to the nearest Emergency Centre.
Manor IVF donor coordinator will contact all donors 48 hours post egg collection for routine follow up

And as always if you have any further questions please contact us derectly or ask via this board

Thank you for reading
ManorIVF team
www.manorivf.com
 
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#3 ·
Gaby2501 said:
Hi can I just ask about donor screening, do you get confirmation of the donors family history and medical history from their family Dr?

Thanks
Hi Gaby,
Thank you for your question.
I have forward your question to oue mediacl team and they answaered :
All donors (in Ukraine) have to provide medical summaries from the following: GP, Gynaecologist, Infectious Diseases Specialist, Endocrinologist, Breast Surgeon.
Regarding their family history they have to sign a statement that the history is clear.

Please let me know if you have got any further qustions

Have a nice evening

ManorIVF team
www.manorivf.com
 
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