Hello!!! Thank you for giving the chance to discuss issues that concern us.
I want to ask you the following: the doctor says that my endometrial lining is always quite thin and that this may be reason I do not get pregnant. Is there anything I can try? What should be the goal?
mainly thin endometrium may be a reason of non-conceiving but it is usually the morphology of the endometrium that matters the most. Pregnancies have been achieved with linings as low as 5.5 mm with trilaminar morphology and good subendometrial blood flow. We prefer an endometrium of 6.5 mm as a minimum with a three layer appearance, but the goal is 8 mm.
There are some supplements that can potentially facilitate this process, i.e. fish oil cps and Q10. Your doctor may change routes (oral, vaginal, transdermal) and dosages of estradiol supplementation, or he/she may use medication outside their original indications (i.e. nifedipine, granulocyte-colony stimulating factor) in order to improve the outcome.
Lately, scratching of the endometrial lining, although still controversial, has been shown to be of some benefit. This sometimes is combined with diagnostic hysteroscopy in order to evaluate the endometrial cavity.
If you have any further questions please do not hesitate to contact us again through our website www.embryolab.eu
The success rate in egg donation program varies, depending on your age, from 55 to 66%. You can have your personal estimated success rate, as long as you would like to have a discussion through skype with our medical team. You can apply now for a free skype consultation in http://www.embryolab.eu/consultation/.
Thank you for your question.
With my husband we have gone through 3 IVF cycles the last 1.5year, with no success.
Is there a point in persevering? Does the success rate alter if we continue?
We are really exhausted...can anyone give advice?
Hope is something you should never lose!!!!!
Age is the main criterion in deciding how to proceed. In women above forty years old success rates decrease with every six months passing, so at some point egg donation IVF may be an option.
In younger women the advice of the embryologist regarding the quality of their embryos is vital. If the couple makes good embryos then persisting is the only way. They may need to change protocols, medications or do extra tests to facilitate further clinical decisions.
It is true though that the more unsuccessful IVF attempts a couple has, the higher the difficulties of getting pregnant become.So, what we do here in Embryolab, in such cases, and what we advise couples to follow, is that we create a detailed personalized protocol of care in order to maximize the couple’s success rates.
Wish you the best of luck for you next attempt!
A normal body mass index is a good starting point. Nowadays it has been acknowledged that increased body weight reduces the success rates of IVF. An overweighed woman will need increased medication dosage which by itself may lead to decreased oocyte quality. She may have changes in endometrial receptivity leading to negative results or even miscarriages.
Even more, most IVF procedures, such as ultrasound scanning, egg retrieval and embryo transfer are much easier and with minimal risks in non- obese patients. Even in men obesity correlates with difficulties in ejaculation and sperm quality.
Smoking is the other denominator a couple has to take into account. It reduces oocyte and sperm quality, changes the immune system with a dramatic drop on the success rates. Within three months of stopping smoking men can see a big improvement in sperm numbers, motility and morphology. There are times that by doing so the IVF process will not be needed.
A healthy diet full of vitamins with lots of fruit, green leaves, raw nuts and proteins will act as an antioxidant for both men and women.
You can always apply for a free skype consultation with our gynecologist, in order to have the chance for a personal discussion and estimation on personal success rates.
Dear Embryolab team!
Going around the forum I have read many of your posts and you seem trustworthy , so I decided to make this post. Maybe you can help me. Let me briefly explain you our history. We have been trying to have a baby for about 2 years . We have done all the necessary tests with our doctor and all seems to be fine. Why can’t I get pregnant then ? And at what point should we start looking towards IVF?
Thanks for taking the time to reply!!
First of all do not loose your hope!
There are plenty of tests that a couple may do before embarking into IVF. Nevertheless all of these are not prerequisites or even necessary. The usual initial tests are a sperm check, a hysterosalpingogram or some other means of checking for tube pathology, such as a lap& dye test, and a hormonal check. Even if these are normal there will be a 20% of the couples that will have unexplained infertility. This does not mean that they do not have a problem. It means that we have not found the reason for their infertility.
When this ‘unexplained’ infertility comes along with female ages of 35 and more then moving towards IVF maybe the answer as ovarian aging may play a significant role. If this happens in younger ages and the subfertility lasts for less than two years then more patience is needed. Some additional tests may be of benefit and timed coitus or intrauterine insemination may help some of these couples. Even in younger couples though, when the pregnancy doesn’t come within 2-3 years of trying, then the advice of a specialist should be sought, as IVF might be the solution.
Dear Embryolab team. Thank you for your quick reply. I know it is really early for asking though I do not have any leave left from work, so how will I manage after the embryo transfer? Do I have to lie down? What are the Do’s and Don’ts?
Thank you for asking. In reality there are not many things you should change after embryo transfer. You can go home the same day with whatever means, no matter how far. That means that you can do an embryo transfer in Greece and travel abroad the same day. Cabin pressures in the plane or car movements on a bad road do not play a role on the outcome.
During the days waiting for the result you should avoid intercourse, hot tub baths or swimming. You don’t need to lie down but you should take it easy and be calm because stress causes uterine spasms. You must behave as being pregnant and not sick, which means that you can do normal household activities but not heavy ones, you can lift small shopping bags, you can have a coffee/tea or you can go for a walk outside.
Keeping stress and anxiety at low levels is the most important thing, so do things that will help you towards that direction.
Do you think that natural IVF/low stimulation protocol is better for women over 43? I am a good responder but my eggs have all resulted in miscarriage. I believe that high dose IVF drugs can damage eggs in older ladies?
If a couple faces male infertility factor the first thing we do is to make a full screen. This screen may contain both blood and sperm tests. These tests include semen analysis, DFI, FSH, Testosterone, Karyotyping, Cystic fibrosis. With the results of the above tests we may propose micro TESE operation or FNA. However for more details on the methods that are used and for giving you a personalized treatment option, you can contact us for a free Skype consultation with our Gynecologist.
What makes Embryolab stand out is our personalized treatment approach. We understand that every couple is unique and need a unique approach. We are against having standard protocols that we apply to everyone, instead we invest time in studying every case individually and we put all our effort in making it a success case. Our success rates really stand out, even though we focus on difficult cases, couples who had failure in the past, we specialize in turning their failure into success.
Another unique element of Embryolab is our quality management system. We have invested into registering processes and procedures in order to eliminate mistakes and ensure quality service.
Most of all, however, we invest in Science itself, which is the core of our IVF unit. Embryolab Academy brings together annually senior doctors and embryologists around the globe. In Embryolab we produce and we apply science so as to offer the best to the couples that trust us.
We would be happy to arrange a free-non binding consultation (skype or facetime) so you can get to know us better.
The dose of medication used depends on the AMH level.
Though in ages over 43 we would prefer higher doses of stimulation, in order to receive a significant amount of eggs.
We will be more than happy though to arrange a free consultation with our doctor, in order to give you a more personalized approach, depending on your personal history as well.
We believe that unique approach is the best way to treat couples in order to have the best possible outcome.
I have been through 7 cycles of ICSI. Had succes on the 4th FET cycle conceiving my daughter in 2011. Have since had 3 more failed cycles trying for a sibling. All along my protocols have been the same, menopur 150 and cetrotide 0,25. I have PCOS and due to this I get good number of mature eggs but after ICSI, the rates are very poor. My embryos on one cycle all not making it after day 1. My question is, is there such a protocol to increase egg quality? As all clinic I have been in contact with suggest to remain on the same meds. Thank you.