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Discussion Starter #1
Hi, just wondering if any of you with low AMH have tried a natural cycle of IVF. After a few failed IVF I'm thinking I might give a natural cycle ago (this will (has) to be my last go). I don't think the high dose stims are having a good effect on my eggs and may be making the quality even worse than they might already be.

Please share your experiences of a natural cycle, what I have read it seems it might be better in my (old) ovaries. Thank you in advance.
Happy
 

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Hi,

There seems to be a few different variations on this type of cycle. I did a natural cycle with low stims on my last two cycles. This consisted of on my first cycle adding low stims on day 6 and on my successful cycle adding low stims on day 3, I also took cetrozide to stop me ovulating. I found on my one and only short protocol with 300 Gonal F and being on the pill beforehand, I had a dominant follicle. Being on the pill prior to an IVF cycle for some ladies with low AMH and high FSH does the opposite of what some people think it does i.e. lowers FSH, it can for some people just over-suppress you and causes dominant follicles. I produced 2 eggs on my first low stim cycle and 5 on my second - I am now pregnant with a singleton. Unfortunately you won't know what suits you until you try it. I found my clinic were very much about tailoring my protocol to me as an individual and I think this is very important. For me, low stims nudged the very few follicles I had along, some people do completely natural ivf with no stim medication and also have great success. I went abroad for my cycles as there was nowhere in the north east that specialised in this and Create in London with all the added extras was way over my budget. Hope this helps, natural IVF/low stim IVF can and does work.

x
 

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Hi janieliz,

I'm crashing a bit here as I was asking you something similar on the cycle buddies thread as you're a north easterner too.  Can you tell me where you went for your cycles abroad, and roughly what it cost and what it involved?
 

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Happy2010, I am in the same situation as you. I have low amh and high fsh 18. I had an Ivf in June, I had only two eggs, only one was fertilised but it was of poor quality and unfortunately did not make it so there was no transfer.

My doctor (I live in Greece) told me that since I did not respond well to drugs the best route to take would be a semi natural cycle with femara and if it does not work then a natural cycle with the egg that my body will choose as the best for fertilisation. If that does not work either then I will resort to DE option.

He told me that poor reponnders have very good results with femara. I trust him 100% so I will follow his advice. If the abovementioned options do not work I will go for DE. At the time being, I take folic acid, vitamin E and cyclacur to calm dowm my ovaries. In September I will see him again and proceed with femara.

Try to think positive. Everything happens for a reason. We will make it in the end. I am 38 and my husband 40.

Wishing you the best!

Rozalia
 

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Thank you rozalia for your response. I think natural/mild is the way to go, good luck with your next cycle. When are you planning on doing the cycle? You sound like you have a good doctor, who you can trust as your interests at heart. Unfortunately I feel like I have been written off due to my very low AMH levels and high FSH.  :'(
 

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Happy2010,

Don't give up! My doctor told me that our task is difficult it is not easy. However, they have seen pregnancies occuring with even higher fsh than mine. He told me that low amh and my fsh does not mean that there are not any good eggs in my ovaries. There are some good eggs too but there are not that many. He told me that he only needs one good egg to make it happen. I also read Greek sites about infertility and many ladies had successful full term pregnancies with semi natural or natural cycles and even with low quality eggs or slow developing eggs.

I think I'll do my second cycle in the end of October. I do it privately so money is always an issue! But I'm determined to do whatever it takes to make it happen. I believe in good psychology and positive thinking too. So, try not to get depressed or when you are feeling down try and do something that you really like. I have my husband and my parents who uplift my spirits when I am down! But it really helps reading about people who experience the same thing as you. It is like our psychotherapy! ;)

Are you thinking of the DE option? In the beginning, I was negative but now I am 100% positive about this option. This option has the most possibilities of becoming pregnant for ladies like us. However, I want to try with my own eggs first and then resort to this option. I'll keep you updated! Please do so too!

 

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Discussion Starter #7
I agree about the positive thinking. After my last cycle (Egg collection Wednesday just gone) I was devastated that my follicles had no eggs. Since reading up on natural IVF it has given me hope that it can work and has made me think more positively. Finances are an issue for me too, thinking early next year to try the natural IVF, I may go for a consultation appointment to see what they say. Also I am going to get my FSH and AMH levels retested to see how bad things have got, this will also influence my decision of trying again.


All the best with your cycle.
 

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Happy, this thread on natural / mild / mini IVF may be helpful for you: http://www.fertilityfriends.co.uk/forum/index.php?topic=331471.0

I'm 41 with AMH of 1.8, when last checked over a year ago, and AFC of 3, and am currently almost 24 weeks pregnant from a mild IVF cycle. (My FSH was only 11.8 the last time I had it tested, so while above optimal levels it was not bad for my age.) I was on 2.5 mg of Femara (aka letrozole) twice per day plus 75 iu Menopur once per day, with no downreg and no GnRH agonist or antagonist except for a couple of doses of Cetrotide near the end to prevent ovulating before EC. I got better results from this cycle, in terms of egg numbers and embryo quality, than from any of my previous cycles with more conventional protocols. I cycled with Reprofit in Czech Republic -- even factoring in all travel costs, UK scans, and some additional tests and immunes treatment I had done, it was half the cost of an IVF cycle in the UK (about £3,000).

Wishing you lots of luck! ^reiki^
 
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