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We have just done a cycle of own sperm / donor eggs, we got 3 blasts and all have been transferred with no successes. The clinic l was happy enough for the 1st transfer, thought we might have got more than 3 blasts though. For the 2nd transfer they seemed very apathetic about it all. There were only changes because l requested some changes e.g. increase progesterone and add Prednisolone.
It is fairly obvious we won't succeed naturally so we are weighing up another round. Im inclined to try another clinic who are more motivated and driven, the current clinic seemed to get quite checked out. They have been increasingly disorganised as well. They are aware the last transfer failed, l have asked to discuss changes for next time to assist us weight up our options. They haven't replied and l am not willing to chase them.
Sorry to hear this. After a few failed cycles clinics want you to leave as it affects their statistics. Make sure you check the sperm and have dna fragmentation done to see if there is an issue there. He might need additional vitamins minerals, life style changes and that could improve your chaces. It takes 3months to make a sperm. Maybe he might need to have antibotics before collection incase there is an underlying issue. Have you checked the timing of the transfer? The moment you loose faith move on. You will find the right clinic.
 

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We had the follow up appointment with our clinic.

They suggested:
-ERA, ALICE and hysteroscopy tests
-no change to our medication (we were 12mg estrofem and 800mg progesterone originally). Last transfer l suggested Prednisolone which they added. If there is a next time then l was going to say more progesterone (up to 1000mg?), Prednisolone again and clexane
-maybe stick with donor maybe change, it is up to us
-he ended the call with a chat about if we ever get pregnant then there is a 5% chance of miscarriage. Which was err super helpful and constructive. Thanks ???

Fairly disappointing. Not helped by him saying our embryo's were 4aa, 3ab and 3ac. We were told / sent an e-mail at the time they were 5aa, 4ab and 3ac. Now wondering if they lied about the quality of the embryos.
I would move if it was me. Not very helpful. I would ask how many eggs were collected and fertiltized. Then you would see if there is an issue with the eggs or sperm. Ask for a copy of your notes as soon as you can.

Definately look at the tests and the hysterscopy.

Ask about Uterine immune profile. This can say if the killer cells are mature enough or too hyper. This way you would have higher levels of progesterone to bring on the immature ones as well as prednisolone to dampen down the natural killer cells.

The ERA for us they found that the transfer should be day 6 not day 5 with extra progesterone.

Also another test is a virginal swab taken and that was high levels of bacteria. They prefer to have high and medium levels of bacteria.

In regards to own sperm. Get this tested for dna fragmentation as well as the general sperm test. This can be improved with diet exercise change in lifestyle as well as no smoking drinking drugs etc.
Takes 3months to improve this.

If the fragmentation is high then you may have an issue with miscarriage if you get pregnant or you may not have blastocysts to transfer. Most clinics forget about the male side.
 
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